
We provide a full, feature‑rich breakdown of the ProtectiveClean 4100, 5100, and 6100 models—so you can confidently choose the best Sonicare toothbrush tailored to your oral care priorities.
1. Overview: Model Hierarchy & Positioning
- ProtectiveClean 4100 – Entry-level; essential cleaning features.

- 5100 – Mid-tier; adds extra cleaning modes and travel convenience.

- 6100 – Premium of the trio; customizable intensities, mode pairing, travel case.

2. Cleaning Modes & Timers
Model | Clean | White | Gum Care | Duration |
---|---|---|---|---|
4100 | ✔ | ❌ | ❌ | 2 min |
5100 | ✔ | ✔ | ✔ | Clean 2 min, White 2:30, Gum 3 min |
6100 | ✔ | ✔ | ✔ | Same as 5100 + 3 intensities |
Additional modes in the 5100 and 6100 enhance whitening (extra 30 s focus) and gum care (gentler, longer session). A built‑in quad‑pacer encourages even brushing.
3. Intensities & Mode Pairing

- Only the 6100 offers three intensity levels (Low/Normal/High) across all modes—ideal for sensitive mouths or shared use.
- The 6100’s BrushSync Mode Pairing automatically selects the optimal mode when detecting a compatible brush head—streamlining usage.
4. Brush Heads Included

- 4100 → C2 Optimal Plaque Control (great for general clean).
- 5100 → G2 Optimal Gum Care (gentler for soft tissue).
- 6100 → W DiamondClean (whitening focus).
All are compatible across models but work best in matching modes (e.g., W head on White mode).
5. BrushSync Reminder & Pressure Sensor

Every model includes:
- RFID BrushSync – automatic brush-head lifespan tracking, alerting replacement after ~3 months or heavy use.
- Pressure Sensor – vibrates handle when brushing too hard.
- 2-minute timer with 30-second quadrant reminders; automatic shut-off ensures full cycle completion.
6. Battery & Travel Convenience

- Battery life: 20+ days on Gum Care, up to 37 days on Clean mode—same across all three.
- Travel case: only the 5100 and 6100 include one.
- Charging stand supports 100–240 V—travel friendly.
7. Design, Grip & Ergonomics

- All handles share a smooth, non-slip matte finish without added rubber grips.
- The 5100/6100 have a dual-button setup with LEDs indicating mode/intensity; the 4100 offers simpler one-button operation.
- A base ridge on the 6100 prevents rolling on counters—small but useful .
8. Pricing & Value Comparison
- 4100: ~$50 – excellent baseline performance.
- 5100: ~$90 – added modes + travel case.
- 6100: ~$110–130 – maximum customization without going flagship‑price.
Industry reviews confirm all three effectively remove plaque; extras in higher models are for comfort and personalization rather than cleaning superiority.
9. Expert & Editorial Highlights
- Tech Gear Lab praises the 4100’s exceptional value: “best value of any toothbrush I have laid hands on,” with nearly 50-day battery life.
- Health.com rates the 4100 as best intro model, and the 6100 as best overall—highlighting three modes and multiple intensities “without extra apps,” delivering a dentist-grade clean.
- Verywell Health emphasizes the 6100’s gum-care mode and pressure sensor, noting long battery life and gentle yet effective clean.
10. Putting It All Together
✅ Who Should Choose Each Model
- ProtectiveClean 4100
• Ideal for budget-conscious users or electric toothbrush newcomers.
• Includes all essential tech—pressure sensor, BrushSync, timer—with only one cleaning mode.
• Top-performing value.
- Removes up to 7x more plaque vs. a manual toothbrush
- Pressure sensor protects teeth and gums from excess brushing pressure
- Always know when to replace your brush head for an effective clean with BrushSync replacement reminder
- ProtectiveClean 5100
• For those desiring whitening and gum health modes.
• Mid‑range pricing and practical travel case.
• No intensity levels.
- Efficient gum care and plaque removal: this electric toothbrush for adults enhances your gum health up to 100% and remov…
- Smart brushing: a pressure sensor that automatically detects pressure you apply, warns you, and reduces the toothbrush v…
- Personalized oral care: Clean mode for superior cleaning, White mode to remove surface stains, and Gum Care mode to gent…
- ProtectiveClean 6100
• Best for those needing adjustable intensity, automatic mode pairing, and a travel case.
• Balanced feature set at approachable pricing—without jumping to flagship “Smart” models.
11. Final Verdict
For most users, the 4100 delivers outstanding cleaning performance at a great price. If you value whitening or gum modes, the 5100 adds convenience without going overboard. For individuals seeking full customization—mode pairing, three intensities, travel case—the 6100 offers premium features at a mid-range price point, making it the best overall pick in the family.
Each model uses the same core sonic motor (31,000 strokes per minute), pressure sensor, and BrushSync technology—so no matter which you choose, you’re backing a trusted, effective Sonicare experience.
12. Clear Summary

- 🎯 4100: Minimalist power, maximum value—simple, effective, affordable.
- 💡 5100: Mode variety + travel convenience = ideal mid-tier choice.
- 🚀 6100: Full customization—great for sensitive teeth, travelers, or those wanting personalized intensity.
Top Recommended Configurations
- Beginners & tight budgets → Sonicare 4100
- Whitening focus → Sonicare 5100
- Personalization + flexibility → Sonicare 6100
Choose the model that suits your lifestyle. Each delivers premium cleaning, professional tech, and long‑lasting battery life—your best smile partner awaits.